RHEB Rabbit Polyclonal Antibody

Description: A Rabbit Polyclonal antibody against RHEB from Human/Mouse/Rat/Cow. This antibody is tested and validated for WB, ELISA, WB, ELISA

Description: A Rabbit Polyclonal antibody against RHEB from Human/Mouse/Rat/Cow. This antibody is tested and validated for WB, ELISA, WB, ELISA

Description: Rabbit polyclonal RHEB antibody

Description: Rabbit polyclonal RHEB antibody raised against the middle region of RHEB

Description: Rheb Antibody: Rheb (Ras homolog enriched in brain) is an evolutionarily conserved member of the Ras family of small GTP-binding proteins originally found to be rapidly induced by synaptic activity in the hippocampus following seizure. While it is expressed at relatively high levels in the brain, Rheb is widely expressed in other tissues and may be induced by growth factor stimulation. Similar to other family members, Rheb triggers activation of the Raf-MEK-MAPK pathway. Biochemical and genetic studies demonstrate that Rheb has an important role in regulating the insulin/Target of rapamycin (TOR) signaling pathway. TOR is a serine/threonine protein kinase that acts as a sensor for ATP and amino acids, balancing the availability of nutrients with protein translation and cell growth. A dimeric protein complex termed TSC1/TSC2 indirectly inhibits TOR activity by inhibiting Rheb via the GAP activity of TSC2.

Description: Rheb Antibody: Rheb (Ras homolog enriched in brain) is an evolutionarily conserved member of the Ras family of small GTP-binding proteins originally found to be rapidly induced by synaptic activity in the hippocampus following seizure. While it is expressed at relatively high levels in the brain, Rheb is widely expressed in other tissues and may be induced by growth factor stimulation. Similar to other family members, Rheb triggers activation of the Raf-MEK-MAPK pathway. Biochemical and genetic studies demonstrate that Rheb has an important role in regulating the insulin/Target of rapamycin (TOR) signaling pathway. TOR is a serine/threonine protein kinase that acts as a sensor for ATP and amino acids, balancing the availability of nutrients with protein translation and cell growth. A dimeric protein complex termed TSC1/TSC2 indirectly inhibits TOR activity by inhibiting Rheb via the GAP activity of TSC2.

Description: Rheb Antibody: Rheb (Ras homolog enriched in brain) is an evolutionarily conserved member of the Ras family of small GTP-binding proteins originally found to be rapidly induced by synaptic activity in the hippocampus following seizure. While it is expressed at relatively high levels in the brain, Rheb is widely expressed in other tissues and may be induced by growth factor stimulation. Similar to other family members, Rheb triggers activation of the Raf-MEK-MAPK pathway. Biochemical and genetic studies demonstrate that Rheb has an important role in regulating the insulin/Target of rapamycin (TOR) signaling pathway. TOR is a serine/threonine protein kinase that acts as a sensor for ATP and amino acids, balancing the availability of nutrients with protein translation and cell growth. A dimeric protein complex termed TSC1/TSC2 indirectly inhibits TOR activity by inhibiting Rheb via the GAP activity of TSC2.

Description: Rheb Antibody: Rheb (Ras homolog enriched in brain) is an evolutionarily conserved member of the Ras family of small GTP-binding proteins originally found to be rapidly induced by synaptic activity in the hippocampus following seizure. While it is expressed at relatively high levels in the brain, Rheb is widely expressed in other tissues and may be induced by growth factor stimulation. Similar to other family members, Rheb triggers activation of the Raf-MEK-MAPK pathway. Biochemical and genetic studies demonstrate that Rheb has an important role in regulating the insulin/Target of rapamycin (TOR) signaling pathway. TOR is a serine/threonine protein kinase that acts as a sensor for ATP and amino acids, balancing the availability of nutrients with protein translation and cell growth. A dimeric protein complex termed TSC1/TSC2 indirectly inhibits TOR activity by inhibiting Rheb via the GAP activity of TSC2.

Description: A polyclonal antibody against RHEB. Recognizes RHEB from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:2000, IHC:1:10-1:50

Description: A polyclonal antibody against RHEB. Recognizes RHEB from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:2000, IHC:1:10-1:50

Description: A polyclonal antibody against RHEB. Recognizes RHEB from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:10000, IHC:1:50-1:200

Description: A polyclonal antibody against RHEB. Recognizes RHEB from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Description: A polyclonal antibody against RHEB. Recognizes RHEB from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:10000, IHC:1:50-1:200

Description: A polyclonal antibody against RHEB. Recognizes RHEB from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200

Description: A polyclonal antibody against RHEB. Recognizes RHEB from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;ELISA:1:1000-1:2000, WB:1:200-1:1000

Description: A polyclonal antibody against RHEB. Recognizes RHEB from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB

Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human RHEB (C-term). This antibody is tested and proven to work in the following applications:

Description: Antibody raised against RHEB

Description: RHEB is a protein encoded by the RHEB gene which is approximately 20,5 kDa. RHEB is localised to the cytoplasm, Golgi apparatus membrane, cytosol and endoplasmic reticulum membrane. It is involved in the regulation of lipid metabolism, insulin signalling-generic cascades, mTOR signalling, RET signalling, AMP-activated protein kinase signalling and the phospholipase D signalling pathway. The RHEB gene is a member of the small GTPase superfamily and encodes the lipid-anchored, cell membrane protein, RHEB. This protein is vital in regulation of growth and cell cycle progression. RHEB is ubiquitous expressed with highest levels observed in skeletal and cardiac muscle. Mutations in the RHEB can result in tuberous sclerosis. STJ98588 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody binds to endogenous levels of RHEB.

Description: This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22.

Description: (NT) Rheb peptide

Description: (IN) Rheb peptide

Description: Mouse polyclonal to RHEB

Description: Mouse polyclonal to RHEB

Description: Rabbit polyclonal to RHEB

Description: Rabbit polyclonal to RHEB

Description: A polyclonal antibody against RHEB. Recognizes RHEB from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

Description: A polyclonal antibody against RHEB. Recognizes RHEB from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

Description: A polyclonal antibody against RHEB. Recognizes RHEB from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

Description: A synthetic peptide for use as a blocking control in assays to test for specificity of RHEB antibody, catalog no. 70R-5794

Description: GTP-Binding Protein Rheb (RHEB) is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. Highest levels of RHEB can be found in the skeletal and cardiac muscle, and it is vital in the regulation of growth and cell cycle progression due to its role in the Insulin/TOR/S6K signaling pathway. RHEB stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling, and it activates the protein kinase activity of mTORC1. RHEB has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, farnesylation of the protein is required for this activity.

Description: A cloning plasmid for the RHEB gene.

Description: A cloning plasmid for the RHEB gene.

Description: Recombinant Human protein for Rheb

Description: Mouse monoclonal to RHEB

Description: Mouse monoclonal to RHEB

Description: Human Rheb (GenBank Accession No. NM_005614), full length with N-terminal His-tag, MW=23 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

Description: A Monoclonal antibody against Human Rheb. The antibodies are raised in Rabbit and are from clone EPR2971. This antibody is applicable in WB and IHC

Description: Lyophilized from a 0.2 μm filtered solution of 20mM Tris, 10mM GSH, pH 8.0.

Description: Lyophilized from a 0.2 μm filtered solution of 20mM Tris, 10mM GSH, pH 8.0.

Description: Lyophilized from a 0.2 μm filtered solution of 20mM Tris, 10mM GSH, pH 8.0.

Description: Lyophilized from a 0.2 μm filtered solution of 20mM Tris, 10mM GSH, pH 8.0.

Description: Purified recombinant Human RheB protein (T7 tag)