GATA-2/3 (Acetyl-Lys336/304) Rabbit Polyclonal Antibody

Description: A polyclonal antibody for detection of GATA-2/3 Acetyl-Lys336/304) from Human, Mouse, Rat. This GATA-2/3 Acetyl-Lys336/304) antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthetic peptide from human protein at AA range: 320-390

Description: A polyclonal antibody for detection of GATA-2/3 Acetyl-Lys336/304) from Human, Mouse, Rat. This GATA-2/3 Acetyl-Lys336/304) antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthetic peptide from human protein at AA range: 320-390

Description: A polyclonal antibody for detection of GATA-2/3 Acetyl-Lys336/304) from Human, Mouse, Rat. This GATA-2/3 Acetyl-Lys336/304) antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthetic peptide from human protein at AA range: 320-390

Description: GATA2 (GATA binding protein 2) encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. The encoded protein plays an essential role in regulating transcription of genes involved in the development and proliferation of hematopoietic and endocrine cell lineages. Alternative splicing results in multiple transcript variants.

Description: GATA2 (GATA binding protein 2) encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. The encoded protein plays an essential role in regulating transcription of genes involved in the development and proliferation of hematopoietic and endocrine cell lineages. Alternative splicing results in multiple transcript variants.

Description: GATA2 (GATA binding protein 2) encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. The encoded protein plays an essential role in regulating transcription of genes involved in the development and proliferation of hematopoietic and endocrine cell lineages. Alternative splicing results in multiple transcript variants.

Description: Human:K336/304;Mouse:K336/304;Rat:K336/305

Description: Human:K336/304;Mouse:K336/304;Rat:K336/305

Description: Available in various conjugation types.

Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Description: disease:Defects in GATA1 are the cause of X-linked dyserythropoietic anemia and thrombocytopenia (XDAT)

Description: disease:Defects in GATA1 are the cause of X-linked dyserythropoietic anemia and thrombocytopenia (XDAT)

Description: disease:Defects in GATA1 are the cause of X-linked dyserythropoietic anemia and thrombocytopenia (XDAT)

Description: Rabbit polyclonal to GATA-2/3 (Acetyl-Lys336/304).

Description: GATA-2/3 (Acetyl-Lys336/304) Rabbit Polyclonal Antibody

Description: GATA-2/3 (Acetyl-Lys336/304) Rabbit Polyclonal Antibody

Description: WB, ELISA

Description: WB, ELISA

Description: Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site| 5'-TTTC

Description: Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site| 5'-TTTC

Description: Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site| 5'-TTTC

Description: disease:Defects in MEF2A might be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1)

Description: disease:Defects in MEF2A might be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1)

Description: disease:Defects in MEF2A might be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1)

Description: The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Several transcript variants encoding different isoforms have been found for this gene. In addition| a polymorphic repeat region is found in the C-terminus of the encoded protein.

Description: The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Several transcript variants encoding different isoforms have been found for this gene. In addition| a polymorphic repeat region is found in the C-terminus of the encoded protein.

Description: The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Several transcript variants encoding different isoforms have been found for this gene. In addition| a polymorphic repeat region is found in the C-terminus of the encoded protein.

Description: WB, ELISA

Description: WB, ELISA

Description: The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein| HMG17| the encoded protein may help maintain an open chromatin configuration around transcribable genes.

Description: The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein| HMG17| the encoded protein may help maintain an open chromatin configuration around transcribable genes.

Description: The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein| HMG17| the encoded protein may help maintain an open chromatin configuration around transcribable genes.

Description: alternative products:At least 4 isoforms| Alpha (shown here)| Alpha-B| Beta and Beta-B| are produced by alternative initiation at Met-1 and Met-27. The existence of isoform Alpha and isoform Alpha-B has been proved by mutagenesis. As the sequence environment of the 2 potential ATG initiator codons is the same for the other altrnatively spliced isoforms| alternative initiation of translation could also occur on these transcripts. Additional isoforms seem to exist|disease:Defects in NR3C1 are a cause of glucocorticoid resistance

Description: alternative products:At least 4 isoforms| Alpha (shown here)| Alpha-B| Beta and Beta-B| are produced by alternative initiation at Met-1 and Met-27. The existence of isoform Alpha and isoform Alpha-B has been proved by mutagenesis. As the sequence environment of the 2 potential ATG initiator codons is the same for the other altrnatively spliced isoforms| alternative initiation of translation could also occur on these transcripts. Additional isoforms seem to exist|disease:Defects in NR3C1 are a cause of glucocorticoid resistance

Description: alternative products:At least 4 isoforms| Alpha (shown here)| Alpha-B| Beta and Beta-B| are produced by alternative initiation at Met-1 and Met-27. The existence of isoform Alpha and isoform Alpha-B has been proved by mutagenesis. As the sequence environment of the 2 potential ATG initiator codons is the same for the other altrnatively spliced isoforms| alternative initiation of translation could also occur on these transcripts. Additional isoforms seem to exist|disease:Defects in NR3C1 are a cause of glucocorticoid resistance

Description: disease:Defects in AR are the cause of androgen insensitivity syndrome (AIS)

Description: disease:Defects in AR are the cause of androgen insensitivity syndrome (AIS)

Description: disease:Defects in AR are the cause of androgen insensitivity syndrome (AIS)

Description: WB, ELISA

Description: WB, ELISA

Description: WB, ELISA

Description: WB, ELISA

Description: WB, ELISA

Description: WB, ELISA

Description: WB, IHC, ELISA

Description: WB, IHC, ELISA

Description: May be the important intermediate by which p53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity| preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression.|induction:By p53| mezerein (antileukemic compound) and interferon beta.|PTM:Phosphorylation of Thr-145 by Akt or of Ser-146 by PKC impairs binding to PCNA.|Belongs to the CDI family.|tissue specificity:Expressed in all adult human tissues| with 5-fold lower levels observed in the brain.|

Description: May be the important intermediate by which p53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity| preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression.|induction:By p53| mezerein (antileukemic compound) and interferon beta.|PTM:Phosphorylation of Thr-145 by Akt or of Ser-146 by PKC impairs binding to PCNA.|Belongs to the CDI family.|tissue specificity:Expressed in all adult human tissues| with 5-fold lower levels observed in the brain.|

Description: May be the important intermediate by which p53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity| preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression.|induction:By p53| mezerein (antileukemic compound) and interferon beta.|PTM:Phosphorylation of Thr-145 by Akt or of Ser-146 by PKC impairs binding to PCNA.|Belongs to the CDI family.|tissue specificity:Expressed in all adult human tissues| with 5-fold lower levels observed in the brain.|

Description: Binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites. Can interact with G/C-rich motifs from serotonin receptor promoter.|PTM:O-glycosylated; contains N-acetylglucosamine side chains.|Belongs to the Sp1 C2H2-type zinc-finger protein family.|Contains 3 C2H2-type zinc fingers.|subunit:Interacts with ATF7IP| ATF7IP2| POGZ| HCFC1| AATF and PHC2. Interacts with varicella-zoster virus IE62 protein and HIV-1 Vpr. Interacts with SV40 VP2/3 proteins. Interacts with SV40 major capsid protein VP1; this interaction leads to a cooperativity between the two proteins in DNA binding.|

Description: Binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites. Can interact with G/C-rich motifs from serotonin receptor promoter.|PTM:O-glycosylated; contains N-acetylglucosamine side chains.|Belongs to the Sp1 C2H2-type zinc-finger protein family.|Contains 3 C2H2-type zinc fingers.|subunit:Interacts with ATF7IP| ATF7IP2| POGZ| HCFC1| AATF and PHC2. Interacts with varicella-zoster virus IE62 protein and HIV-1 Vpr. Interacts with SV40 VP2/3 proteins. Interacts with SV40 major capsid protein VP1; this interaction leads to a cooperativity between the two proteins in DNA binding.|

Description: Binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites. Can interact with G/C-rich motifs from serotonin receptor promoter.|PTM:O-glycosylated; contains N-acetylglucosamine side chains.|Belongs to the Sp1 C2H2-type zinc-finger protein family.|Contains 3 C2H2-type zinc fingers.|subunit:Interacts with ATF7IP| ATF7IP2| POGZ| HCFC1| AATF and PHC2. Interacts with varicella-zoster virus IE62 protein and HIV-1 Vpr. Interacts with SV40 VP2/3 proteins. Interacts with SV40 major capsid protein VP1; this interaction leads to a cooperativity between the two proteins in DNA binding.|

Description: YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter| thus implicating histone modification in the function of YY1.

Description: YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter| thus implicating histone modification in the function of YY1.

Description: YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter| thus implicating histone modification in the function of YY1.

Description: cofactor:Binds 1 zinc ion per subunit.|disease:Defects in TP53 are a cause of choroid plexus papilloma

Description: cofactor:Binds 1 zinc ion per subunit.|disease:Defects in TP53 are a cause of choroid plexus papilloma

Description: cofactor:Binds 1 zinc ion per subunit.|disease:Defects in TP53 are a cause of choroid plexus papilloma

Description: The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus| it functions as a regulator of a wide variety of downstream proteins| including tumor suppressor proteins p53 and BRCA1| checkpoint kinase CHK2| checkpoint proteins RAD17 and RAD9| and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia| an autosomal recessive disorder.

Description: The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus| it functions as a regulator of a wide variety of downstream proteins| including tumor suppressor proteins p53 and BRCA1| checkpoint kinase CHK2| checkpoint proteins RAD17 and RAD9| and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia| an autosomal recessive disorder.

Description: The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus| it functions as a regulator of a wide variety of downstream proteins| including tumor suppressor proteins p53 and BRCA1| checkpoint kinase CHK2| checkpoint proteins RAD17 and RAD9| and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia| an autosomal recessive disorder.

Description: This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains| and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene| and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms| resulting from the use of alternate downstream translation initiation sites| have also been noted. A related pseudogene has been identified on chromosome 13.

Description: This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains| and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene| and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms| resulting from the use of alternate downstream translation initiation sites| have also been noted. A related pseudogene has been identified on chromosome 13.

Description: This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains| and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene| and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms| resulting from the use of alternate downstream translation initiation sites| have also been noted. A related pseudogene has been identified on chromosome 13.

Description: disease:Defects in SRY are a cause of gonadal dysgenesis XY female type (GDXY)

Description: disease:Defects in SRY are a cause of gonadal dysgenesis XY female type (GDXY)

Description: disease:Defects in SRY are a cause of gonadal dysgenesis XY female type (GDXY)

Description: WB, IHC, IF, ELISA

Description: WB, IHC, IF, ELISA

Description: WB, ELISA

Description: WB, ELISA

Description: WB, ELISA

Description: WB, ELISA

Description: WB, IHC, ELISA

Description: WB, IHC, ELISA

Description: WB, IHC, ELISA