Gab 2 (phospho Ser159) Rabbit Polyclonal Antibody

Description: A polyclonal antibody for detection of Gab 2 phospho Ser159) from Human, Mouse, Rat. This Gab 2 phospho Ser159) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Gab 2 around the phosphorylation site of S159

Description: This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.

Description: This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.

Description: This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.

Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Description: Available in various conjugation types.

Description: WB, IHC, ELISA

Description: WB, IHC, ELISA

Description: WB, IF, ELISA

Description: WB, IF, ELISA

Description: A polyclonal antibody for detection of Gab 2 phospho Ser623) from Human, Mouse, Rat. This Gab 2 phospho Ser623) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Gab 2 around the phosphorylation site of S623

Description: A polyclonal antibody for detection of Gab 2 phospho Ser623) from Human, Mouse, Rat. This Gab 2 phospho Ser623) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Gab 2 around the phosphorylation site of S623

Description: A polyclonal antibody for detection of Gab 2 phospho Ser623) from Human, Mouse, Rat. This Gab 2 phospho Ser623) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Gab 2 around the phosphorylation site of S623

Description: This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.

Description: This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.

Description: This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.

Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Description: Available in various conjugation types.

Description: WB, ELISA

Description: WB, ELISA

Description: WB, IHC, ELISA

Description: WB, IHC, ELISA

Description: WB, IHC, IF, ELISA

Description: WB, IHC, IF, ELISA

Description: IHC, ELISA

Description: IHC, ELISA

Description: WB, ELISA

Description: WB, ELISA

Description: The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems| which regulate the release of neurotransmitters| and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1| neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.

Description: The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems| which regulate the release of neurotransmitters| and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1| neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.

Description: The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems| which regulate the release of neurotransmitters| and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1| neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.

Description: WB, IHC, ELISA

Description: WB, IHC, ELISA

Description: WB, ELISA

Description: WB, ELISA

Description: A polyclonal antibody for detection of Mcl-1 phospho Ser159) from Human, Mouse. This Mcl-1 phospho Ser159) antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Mcl-1 around the phosphorylation site of S159

Description: A polyclonal antibody for detection of Mcl-1 phospho Ser159) from Human, Mouse. This Mcl-1 phospho Ser159) antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Mcl-1 around the phosphorylation site of S159

Description: A polyclonal antibody for detection of Mcl-1 phospho Ser159) from Human, Mouse. This Mcl-1 phospho Ser159) antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Mcl-1 around the phosphorylation site of S159

Description: This gene encodes an anti-apoptotic protein| which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.

Description: This gene encodes an anti-apoptotic protein| which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.

Description: This gene encodes an anti-apoptotic protein| which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.

Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Description: Available in various conjugation types.

Description: IHC, ELISA

Description: IHC, ELISA

Description: WB, IHC, IF, ELISA

Description: WB, IHC, IF, ELISA

Description: IHC, ELISA

Description: IHC, ELISA

Description: WB, IHC, IP, ELISA

Description: WB, IHC, IP, ELISA

Description: WB, IHC, IF, ELISA

Description: WB, IHC, IF, ELISA

Description: WB, IHC, ELISA

Description: WB, IHC, ELISA

Description: WB, IHC, ELISA

Description: WB, IHC, ELISA

Description: IHC, ELISA

Description: IHC, ELISA

Description: WB, ELISA

Description: WB, ELISA

Description: WB, ELISA

Description: WB, ELISA

Description: WB, ELISA

Description: WB, ELISA

Description: WB, IHC, ELISA

Description: WB, IHC, ELISA

Description: WB, IHC, ELISA

Description: WB, IHC, ELISA

Description: WB, IHC, ELISA

Description: WB, IHC, ELISA

Description: WB, ELISA

Description: WB, ELISA

Description: WB, IHC, IP, ELISA

Description: WB, IHC, IP, ELISA

Description: WB, IHC, IP, ELISA

Description: WB, IHC, IP, ELISA

Description: IHC, ELISA

Description: IHC, ELISA

Description: WB, IHC, ELISA

Description: WB, IHC, ELISA

Description: The calpains| calcium-activated neutral proteases| are nonlysosomal| intracellular cysteine proteases. The mammalian calpains include ubiquitous| stomach-specific| and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large| catalytic subunits associated with a common small| regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme| calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported. Two transcript variants encoding different isoforms have been found for this gene.

Description: The calpains| calcium-activated neutral proteases| are nonlysosomal| intracellular cysteine proteases. The mammalian calpains include ubiquitous| stomach-specific| and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large| catalytic subunits associated with a common small| regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme| calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported. Two transcript variants encoding different isoforms have been found for this gene.

Description: The calpains| calcium-activated neutral proteases| are nonlysosomal| intracellular cysteine proteases. The mammalian calpains include ubiquitous| stomach-specific| and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large| catalytic subunits associated with a common small| regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme| calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported. Two transcript variants encoding different isoforms have been found for this gene.

Description: cofactor:NAD. Required for efficient interaction with E1A. Cofactor binding induces a conformation change.|Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex (By similarity). Co-repressor targeting diverse transcription regulators such as GLIS2. Has dehydrogenase activity.|PTM:ADP-ribosylated; when cells are exposed to brefeldin-A (BFA).|PTM:Sumoylation on Lys-428 is promoted by the E3 SUMO-protein ligase CBX4.|PTM:The level of phosphorylation appears to be regulated during the cell cycle. Phosphorylated upon DNA damage| probably by ATM or ATR. Phosphorylation by HIPK2 on Ser-422 induces proteasomal degradation.|Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|subunit:Interacts with the C-terminus of adenovirus E1A protein| ELK3 and CTIP via their consensus motif P-X-

Description: cofactor:NAD. Required for efficient interaction with E1A. Cofactor binding induces a conformation change.|Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex (By similarity). Co-repressor targeting diverse transcription regulators such as GLIS2. Has dehydrogenase activity.|PTM:ADP-ribosylated; when cells are exposed to brefeldin-A (BFA).|PTM:Sumoylation on Lys-428 is promoted by the E3 SUMO-protein ligase CBX4.|PTM:The level of phosphorylation appears to be regulated during the cell cycle. Phosphorylated upon DNA damage| probably by ATM or ATR. Phosphorylation by HIPK2 on Ser-422 induces proteasomal degradation.|Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|subunit:Interacts with the C-terminus of adenovirus E1A protein| ELK3 and CTIP via their consensus motif P-X-

Description: cofactor:NAD. Required for efficient interaction with E1A. Cofactor binding induces a conformation change.|Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex (By similarity). Co-repressor targeting diverse transcription regulators such as GLIS2. Has dehydrogenase activity.|PTM:ADP-ribosylated; when cells are exposed to brefeldin-A (BFA).|PTM:Sumoylation on Lys-428 is promoted by the E3 SUMO-protein ligase CBX4.|PTM:The level of phosphorylation appears to be regulated during the cell cycle. Phosphorylated upon DNA damage| probably by ATM or ATR. Phosphorylation by HIPK2 on Ser-422 induces proteasomal degradation.|Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|subunit:Interacts with the C-terminus of adenovirus E1A protein| ELK3 and CTIP via their consensus motif P-X-

Description: WB, IHC, ELISA

Description: WB, IHC, ELISA

Description: WB, IHC, ELISA

Description: WB, IHC, ELISA

Description: WB, IHC, ELISA

Description: WB, IHC, ELISA