E2F-1 (Acetyl-Lys120) Rabbit Polyclonal Antibody

Description: Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site| 5'-TTTC

Description: Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site| 5'-TTTC

Description: Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site| 5'-TTTC

Description: WB, ELISA

Description: WB, ELISA

Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A| H2B| H3| and H4) form an octamer| around which approximately 146 bp of DNA is wrapped in repeating units| called nucleosomes. The linker histone| H1| interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.

Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A| H2B| H3| and H4) form an octamer| around which approximately 146 bp of DNA is wrapped in repeating units| called nucleosomes. The linker histone| H1| interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.

Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A| H2B| H3| and H4) form an octamer| around which approximately 146 bp of DNA is wrapped in repeating units| called nucleosomes. The linker histone| H1| interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.

Description: A polyclonal antibody for detection of E2F-1 Acetyl-Lys120) from Human, Mouse, Rat. This E2F-1 Acetyl-Lys120) antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthetic peptide from human protein at AA range: 100-170

Description: A polyclonal antibody for detection of E2F-1 Acetyl-Lys120) from Human, Mouse, Rat. This E2F-1 Acetyl-Lys120) antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthetic peptide from human protein at AA range: 100-170

Description: A polyclonal antibody for detection of E2F-1 Acetyl-Lys120) from Human, Mouse, Rat. This E2F-1 Acetyl-Lys120) antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthetic peptide from human protein at AA range: 100-170

Description: The protein encoded by E2F1 (E2F transcription factor 1) is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis.

Description: The protein encoded by E2F1 (E2F transcription factor 1) is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis.

Description: The protein encoded by E2F1 (E2F transcription factor 1) is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis.

Description: Human:K120;Mouse:K115;Rat:K118

Description: Human:K120;Mouse:K115;Rat:K118

Description: Available in various conjugation types.

Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Description: WB, ELISA

Description: WB, ELISA

Description: A polyclonal antibody for detection of E2F-4 Acetyl Lys96) from Human, Mouse, Rat. This E2F-4 Acetyl Lys96) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the human E2F-4 around the acetylation site of K96

Description: A polyclonal antibody for detection of E2F-4 Acetyl Lys96) from Human, Mouse, Rat. This E2F-4 Acetyl Lys96) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the human E2F-4 around the acetylation site of K96

Description: A polyclonal antibody for detection of E2F-4 Acetyl Lys96) from Human, Mouse, Rat. This E2F-4 Acetyl Lys96) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the human E2F-4 around the acetylation site of K96

Description: The protein encoded by E2F4 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. E2F transcription factor 4 binds to all three of the tumor suppressor proteins pRB, p107 and p130, but with higher affinity to the last two. It plays an important role in the suppression of proliferation-associated genes, and its gene mutation and increased expression may be associated with human cancer.

Description: The protein encoded by E2F4 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. E2F transcription factor 4 binds to all three of the tumor suppressor proteins pRB, p107 and p130, but with higher affinity to the last two. It plays an important role in the suppression of proliferation-associated genes, and its gene mutation and increased expression may be associated with human cancer.

Description: The protein encoded by E2F4 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. E2F transcription factor 4 binds to all three of the tumor suppressor proteins pRB, p107 and p130, but with higher affinity to the last two. It plays an important role in the suppression of proliferation-associated genes, and its gene mutation and increased expression may be associated with human cancer.

Description: Human;Mouse;Rat

Description: Human;Mouse;Rat

Description: Available in various conjugation types.

Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Description: This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex| which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain| placenta| lung| liver| kidney| and pancreas| and the other isoform (alpha 2) is expressed in brain| heart and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome. This gene has been found to have multiple copies on many chromosomes| some of which| if not all| represent different pseudogenes.

Description: This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex| which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain| placenta| lung| liver| kidney| and pancreas| and the other isoform (alpha 2) is expressed in brain| heart and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome. This gene has been found to have multiple copies on many chromosomes| some of which| if not all| represent different pseudogenes.

Description: This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex| which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain| placenta| lung| liver| kidney| and pancreas| and the other isoform (alpha 2) is expressed in brain| heart and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome. This gene has been found to have multiple copies on many chromosomes| some of which| if not all| represent different pseudogenes.

Description: WB, ELISA

Description: WB, ELISA

Description: WB, ELISA

Description: WB, ELISA

Description: disease:Defects in GATA1 are the cause of X-linked dyserythropoietic anemia and thrombocytopenia (XDAT)

Description: disease:Defects in GATA1 are the cause of X-linked dyserythropoietic anemia and thrombocytopenia (XDAT)

Description: disease:Defects in GATA1 are the cause of X-linked dyserythropoietic anemia and thrombocytopenia (XDAT)

Description: Binds preferentially single-stranded DNA and unwinds double stranded DNA.|Belongs to the HMGB family.|Contains 2 HMG box DNA-binding domains.|

Description: Binds preferentially single-stranded DNA and unwinds double stranded DNA.|Belongs to the HMGB family.|Contains 2 HMG box DNA-binding domains.|

Description: Binds preferentially single-stranded DNA and unwinds double stranded DNA.|Belongs to the HMGB family.|Contains 2 HMG box DNA-binding domains.|

Description: WB, IHC, ELISA

Description: WB, IHC, ELISA

Description: E2F-1 is a protein encoded by the E2F1 gene which is approximately 46,9 kDa. E2F-1 is localised to the nucleus. It is involved in glioma, cyclins and cell cycle regulation and activation of BH3-only proteins. It plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. E2F-1 is expressed in the skin, pancreas and the nervous system. Mutations in the E2F1 gene may result in retinoblastoma pharyngoconjunctival fever. STJ97800 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody detects endogenous levels of E2F-1 (Acetyl Lys120).

Description: WB, ELISA

Description: WB, ELISA

Description: WB, ELISA

Description: WB, ELISA

Description: WB, ELISA

Description: WB, ELISA

Description: Binds preferentially single-stranded DNA and unwinds double stranded DNA.|Belongs to the HMGB family.|Contains 2 HMG box DNA-binding domains.|

Description: Binds preferentially single-stranded DNA and unwinds double stranded DNA.|Belongs to the HMGB family.|Contains 2 HMG box DNA-binding domains.|

Description: Binds preferentially single-stranded DNA and unwinds double stranded DNA.|Belongs to the HMGB family.|Contains 2 HMG box DNA-binding domains.|

Description: WB, IHC, ELISA

Description: WB, IHC, ELISA

Description: WB, ELISA

Description: WB, ELISA

Description: alternative products:At least 4 isoforms| Alpha (shown here)| Alpha-B| Beta and Beta-B| are produced by alternative initiation at Met-1 and Met-27. The existence of isoform Alpha and isoform Alpha-B has been proved by mutagenesis. As the sequence environment of the 2 potential ATG initiator codons is the same for the other altrnatively spliced isoforms| alternative initiation of translation could also occur on these transcripts. Additional isoforms seem to exist|disease:Defects in NR3C1 are a cause of glucocorticoid resistance

Description: alternative products:At least 4 isoforms| Alpha (shown here)| Alpha-B| Beta and Beta-B| are produced by alternative initiation at Met-1 and Met-27. The existence of isoform Alpha and isoform Alpha-B has been proved by mutagenesis. As the sequence environment of the 2 potential ATG initiator codons is the same for the other altrnatively spliced isoforms| alternative initiation of translation could also occur on these transcripts. Additional isoforms seem to exist|disease:Defects in NR3C1 are a cause of glucocorticoid resistance

Description: alternative products:At least 4 isoforms| Alpha (shown here)| Alpha-B| Beta and Beta-B| are produced by alternative initiation at Met-1 and Met-27. The existence of isoform Alpha and isoform Alpha-B has been proved by mutagenesis. As the sequence environment of the 2 potential ATG initiator codons is the same for the other altrnatively spliced isoforms| alternative initiation of translation could also occur on these transcripts. Additional isoforms seem to exist|disease:Defects in NR3C1 are a cause of glucocorticoid resistance

Description: disease:Defects in AR are the cause of androgen insensitivity syndrome (AIS)

Description: disease:Defects in AR are the cause of androgen insensitivity syndrome (AIS)

Description: disease:Defects in AR are the cause of androgen insensitivity syndrome (AIS)

Description: WB, ELISA

Description: WB, ELISA